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Furaptra(Mag-Fura-2),Tetrapotassium salt
Product overview:
Parameters
Appearance: Light yellow solid soluble in water (PH > 6)
CAS No.: 132319-57-4
Molecular Formula: C18H10K4N2O11
Molecular Weight: 587
Storage
Store at -20°C and protect from light. When stored as directed, product is stable for at least 12 months.
Description
Mag-Fura-2 is a UV-excitable fluorescent indicator for magnesium with a Kd of 1.9 mM. Similar to Fura-2, the excitation wavelength of Mag-Fura-2 undergoes a blue shift from 369 nm to 330 nm. Mag-Fura-2 also responds to Ca2+ but with a significantly higher Kd than Fura-2 for Ca2+. An important application of Mag-Fura-2 is its use in detecting high, transient Ca2+ concentration during Ca2+ spikes. Mag-Fura-2/tetraammonium salt can be loaded into cells by microinjection or scrape loading.
Notes
1. Mg2+ indicators are sensitive to Mg2+ concentrations from 0.1 to 10 mM and Ca2+ concentrations from 1 to 100 mM.
2. Zn2+ , Cd2+ and Gd3+ can also bind to the fluorescent indicator, which may interfere with the experiment.